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Fixing frataxin: ‘ironing out’ the metabolic defect in Friedreich's ataxia
The metabolically active and redox-active mitochondrion appears to play a major role in the cellular metabolism of the transition metal, iron. Frataxin, a mitochondrial matrix protein, has been identified as playing a key role in the iron metabolism of this organelle due to its iron-binding properti...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Blackwell Publishing Ltd
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976629/ https://ncbi.nlm.nih.gov/pubmed/24138602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12470 |
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