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Fixing frataxin: ‘ironing out’ the metabolic defect in Friedreich's ataxia
The metabolically active and redox-active mitochondrion appears to play a major role in the cellular metabolism of the transition metal, iron. Frataxin, a mitochondrial matrix protein, has been identified as playing a key role in the iron metabolism of this organelle due to its iron-binding properti...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Blackwell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976629/ https://ncbi.nlm.nih.gov/pubmed/24138602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12470 |
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