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Mitochondrial metals as a potential therapeutic target in neurodegeneration
Transition metals are critical for enzyme function and protein folding, but in excess can mediate neurotoxic oxidative processes. As mitochondria are particularly vulnerable to oxidative damage due to radicals generated during ATP production, mitochondrial biometal homeostasis must therefore be tigh...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976628/ https://ncbi.nlm.nih.gov/pubmed/24206195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12513 |
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