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Autophagy and mitophagy in the myocardium: therapeutic potential and concerns

The autophagic-lysosomal degradation pathway is critical for cardiac homeostasis, and defects in this pathway are associated with development of cardiomyopathy. Autophagy is responsible for the normal turnover of organelles and long-lived proteins. Autophagy is also rapidly up-regulated in response...

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Autors principals: Jimenez, Rebecca E, Kubli, Dieter A, Gustafsson, Åsa B
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976612/
https://ncbi.nlm.nih.gov/pubmed/24148024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12477
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