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Autophagy and mitophagy in the myocardium: therapeutic potential and concerns

The autophagic-lysosomal degradation pathway is critical for cardiac homeostasis, and defects in this pathway are associated with development of cardiomyopathy. Autophagy is responsible for the normal turnover of organelles and long-lived proteins. Autophagy is also rapidly up-regulated in response...

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Autori principali: Jimenez, Rebecca E, Kubli, Dieter A, Gustafsson, Åsa B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976612/
https://ncbi.nlm.nih.gov/pubmed/24148024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12477
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