Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors.
4 beta-Phorbol 12-myristate 13-acetate (PMA) treatment of KB cells at 37 degrees C rapidly induces a 50% reduction in epidermal growth factor (EGF) binding that is maximal by 30 min. EGF binding activity returns to the original value by 1 hr and remains constant for 2 hr thereafter. Using a polyclon...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1985
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397648/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2859591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.9.2774 |
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