Ca(V)3.2 T-Type Calcium Channels in Peripheral Sensory Neurons Are Important for Mibefradil-Induced Reversal of Hyperalgesia and Allodynia in Rats with Painful Diabetic Neuropathy

We recently showed that streptozotocin (STZ) injections in rats lead to the development of painful peripheral diabetic neuropathy (PDN) accompanied by enhancement of Ca(V)3.2 T-type calcium currents (T-currents) and hyperexcitability in dorsal root ganglion (DRG) neurons. Here we used the classical...

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Detalhes bibliográficos
Main Authors: Obradovic, Aleksandar Lj., Hwang, Sung Mi, Scarpa, Joseph, Hong, Sung Jun, Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976247/
https://ncbi.nlm.nih.gov/pubmed/24705276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091467
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