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Selective inhibition of Ca(v)3.2 channels reverses hyperexcitability of peripheral nociceptors and alleviates post-surgical pain
Pain-sensing sensory neurons of the dorsal root ganglion (DRG) can become sensitized (hyperexcitable) in response to surgically-induced peripheral tissue injury. However, the potential role and molecular mechanisms of nociceptive ion channel dysregulation in acute pain conditions such as those resul...
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| Publicado no: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6193449/ https://ncbi.nlm.nih.gov/pubmed/30154101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aao4425 |
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