The Role of Free Oxygen Radicals in Lasting Hyperexcitability of Rat Subicular Neurons After Exposure to General Anesthesia During Brain Development

A large number of preclinical studies have established that general anesthetics (GAs) may cause neurodevelopmental toxicity in rodents and nonhuman primates, which is followed by long-term cognitive deficits. The subiculum, the main output structure of hippocampal formation, is one of the brain regi...

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Veröffentlicht in:Mol Neurobiol
Hauptverfasser: Joksimovic, Srdjan M., DiGruccio, Michael R., Boscolo, Annalisa, Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7273833/
https://ncbi.nlm.nih.gov/pubmed/31493241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-019-01770-y
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