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Expression, purification, crystallization and preliminary X-ray diffraction analysis of a mammalian type 10 adenylyl cyclase

The second messenger cAMP is synthesized in mammals by ten differently regulated adenylyl cyclases (AC1–10). These ACs are grouped into nucleotidyl cyclase class III based on homologies in their catalytic domains. The catalytic domain of AC10 is unique, however, in being activated through direct int...

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Bibliografiset tiedot
Päätekijät: Kleinboelting, Silke, van den Heuvel, Joop, Kambach, Christian, Weyand, Michael, Leipelt, Martina, Steegborn, Clemens
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Union of Crystallography 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976064/
https://ncbi.nlm.nih.gov/pubmed/24699740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14004014
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