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A KcsA/MloK1 Chimeric Ion Channel Has Lipid-dependent Ligand-binding Energetics
Cyclic nucleotide-modulated ion channels play crucial roles in signal transduction in eukaryotes. The molecular mechanism by which ligand binding leads to channel opening remains poorly understood, due in part to the lack of a robust method for preparing sufficient amounts of purified, stable protei...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975005/ https://ncbi.nlm.nih.gov/pubmed/24515111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.543389 |
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