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A hydrolase of trehalose dimycolate induces nutrient influx and stress sensitivity to balance intracellular growth of Mycobacterium tuberculosis
Chronic tuberculosis in an immunocompetent host is a consequence of the delicately balanced growth of Mycobacterium tuberculosis (Mtb) in the face of host defense mechanisms. We identify an Mtb enzyme (Tdmh(Mtb)) that hydrolyzes the mycobacterial glycolipid trehalose dimycolate and plays a critical...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974621/ https://ncbi.nlm.nih.gov/pubmed/24528862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.01.008 |
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