Denervation atrophy is independent from Akt and mTOR activation and is not rescued by myostatin inhibition

The purpose of our study was to compare two acquired muscle atrophies and the use of myostatin inhibition for their treatment. Myostatin naturally inhibits skeletal muscle growth by binding to ActRIIB, a receptor on the cell surface of myofibers. Because blocking myostatin in an adult wild-type mous...

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Detaylı Bibliyografya
Asıl Yazarlar: MacDonald, Elizabeth M., Andres-Mateos, Eva, Mejias, Rebeca, Simmers, Jessica L., Mi, Ruifa, Park, Jae-Sung, Ying, Stephanie, Hoke, Ahmet, Lee, Se-Jin, Cohn, Ronald D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Limited 2014
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974457/
https://ncbi.nlm.nih.gov/pubmed/24504412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.014126
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