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Pharmacophore and Virtual Screening of JAK3 inhibitors

Janus kinase 3 (JAK3) is a non-receptor tyrosine kinases family of protein which is comprised of JAK1, JAK2, JAK3 and TYK2. It plays an important role in immune function and lymphoid development and it only resides in the hematopoietic system. Therefore, selective targeting JAK3 is a rational approa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rajeswari, Murugesan, Santhi, Natchimuthu, Bhuvaneswari, Vembu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biomedical Informatics 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974243/
https://ncbi.nlm.nih.gov/pubmed/24748756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010157
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