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Pharmacophore and Virtual Screening of JAK3 inhibitors
Janus kinase 3 (JAK3) is a non-receptor tyrosine kinases family of protein which is comprised of JAK1, JAK2, JAK3 and TYK2. It plays an important role in immune function and lymphoid development and it only resides in the hematopoietic system. Therefore, selective targeting JAK3 is a rational approa...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Biomedical Informatics
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974243/ https://ncbi.nlm.nih.gov/pubmed/24748756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010157 |
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