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Pharmacophore and Virtual Screening of JAK3 inhibitors

Janus kinase 3 (JAK3) is a non-receptor tyrosine kinases family of protein which is comprised of JAK1, JAK2, JAK3 and TYK2. It plays an important role in immune function and lymphoid development and it only resides in the hematopoietic system. Therefore, selective targeting JAK3 is a rational approa...

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Detaylı Bibliyografya
Asıl Yazarlar: Rajeswari, Murugesan, Santhi, Natchimuthu, Bhuvaneswari, Vembu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Biomedical Informatics 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974243/
https://ncbi.nlm.nih.gov/pubmed/24748756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010157
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