Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice

BACKGROUND: Extraneuronal levels of the neurotransmitter glutamate in brain rise during aging. This is thought to lead to synaptic dysfunction and neuronal injury or death. To study the effects of glutamate hyperactivity in brain, we created transgenic (Tg) mice in which the gene for glutamate dehyd...

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Bibliografski detalji
Glavni autori: Wang, Xinkun, Patel, Nilam D, Hui, Dongwei, Pal, Ranu, Hafez, Mohamed M, Sayed-Ahmed, Mohamed M, Al-Yahya, Abdulaziz A, Michaelis, Elias K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973933/
https://ncbi.nlm.nih.gov/pubmed/24593767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-37
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