Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice

BACKGROUND: Extraneuronal levels of the neurotransmitter glutamate in brain rise during aging. This is thought to lead to synaptic dysfunction and neuronal injury or death. To study the effects of glutamate hyperactivity in brain, we created transgenic (Tg) mice in which the gene for glutamate dehyd...

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Main Authors: Wang, Xinkun, Patel, Nilam D, Hui, Dongwei, Pal, Ranu, Hafez, Mohamed M, Sayed-Ahmed, Mohamed M, Al-Yahya, Abdulaziz A, Michaelis, Elias K
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973933/
https://ncbi.nlm.nih.gov/pubmed/24593767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-37
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