Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice

BACKGROUND: Extraneuronal levels of the neurotransmitter glutamate in brain rise during aging. This is thought to lead to synaptic dysfunction and neuronal injury or death. To study the effects of glutamate hyperactivity in brain, we created transgenic (Tg) mice in which the gene for glutamate dehyd...

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Autores principales: Wang, Xinkun, Patel, Nilam D, Hui, Dongwei, Pal, Ranu, Hafez, Mohamed M, Sayed-Ahmed, Mohamed M, Al-Yahya, Abdulaziz A, Michaelis, Elias K
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973933/
https://ncbi.nlm.nih.gov/pubmed/24593767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-37
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