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Metabolism Changes During Aging in the Hippocampus and Striatum of Glud1 (Glutamate Dehydrogenase 1) Transgenic Mice

The decline in neuronal function during aging may result from increases in extracellular glutamate (Glu), Glu-induced neurotoxicity, and altered mitochondrial metabolism. To study metabolic responses to persistently high levels of Glu at synapses during aging, we used transgenic (Tg) mice that over-...

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Detalhes bibliográficos
Main Authors: Choi, In-Young, Lee, Phil, Wang, Wen-Tung, Hui, Dongwei, Wang, Xinkun, Brooks, William M., Michaelis, Elias K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4095984/
https://ncbi.nlm.nih.gov/pubmed/24442550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-014-1239-9
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