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Tempol prevents genotoxicity induced by vorinostat: role of oxidative DNA damage

Vorinostat is a member of histone deacetylase inhibitors, which represents a new class of anticancer agents for the treatment of solid and hematological malignancies. Studies have shown that these drugs induce DNA damage in blood lymphocytes, which is proposed to be due to the generation of oxidativ...

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Bibliografske podrobnosti
Main Authors: Alzoubi, Karem H., Khabour, Omar F., Jaber, Aya G., Al-azzam, Sayer I., Mhaidat, Nizar M., Masadeh, Majed M.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973794/
https://ncbi.nlm.nih.gov/pubmed/23761013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9597-8
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