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Tempol prevents genotoxicity induced by vorinostat: role of oxidative DNA damage

Vorinostat is a member of histone deacetylase inhibitors, which represents a new class of anticancer agents for the treatment of solid and hematological malignancies. Studies have shown that these drugs induce DNA damage in blood lymphocytes, which is proposed to be due to the generation of oxidativ...

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Detalles Bibliográficos
Main Authors: Alzoubi, Karem H., Khabour, Omar F., Jaber, Aya G., Al-azzam, Sayer I., Mhaidat, Nizar M., Masadeh, Majed M.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973794/
https://ncbi.nlm.nih.gov/pubmed/23761013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9597-8
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