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Tempol prevents genotoxicity induced by vorinostat: role of oxidative DNA damage
Vorinostat is a member of histone deacetylase inhibitors, which represents a new class of anticancer agents for the treatment of solid and hematological malignancies. Studies have shown that these drugs induce DNA damage in blood lymphocytes, which is proposed to be due to the generation of oxidativ...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer Netherlands
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973794/ https://ncbi.nlm.nih.gov/pubmed/23761013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9597-8 |
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