Ciprofloxacin-Induced Antibacterial Activity Is Attenuated by Phosphodiesterase Inhibitors

BACKGROUND: Ciprofloxacin is a commonly used antibiotic for urinary tract infection that interacts with bacterial topoisomerases leading to oxidative radicals generation and bacterial cell death. Phosphodiesterase inhibitors (PDEis), on the other hand, are commonly used drugs for the management of e...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Ther Res Clin Exp
Hauptverfasser: Masadeh, Majed M., Alzoubi, Karem H., Khabour, Omar F., Al-Azzam, Sayer I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644238/
https://ncbi.nlm.nih.gov/pubmed/26649077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2014.11.001
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