Sustained stabilization of Interleukin-8 mRNA in human macrophages

The mRNAs of most inflammatory mediators are short-lived due to AU-rich elements (AREs) in their 3′-untranslated regions. AREs ensure a low basal level of expression during homeostasis and a transient nature of expression during the inflammatory response. Here, we report that the mRNA of the pro-inf...

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Autores principales: Mahmoud, Linah, Al-Enezi, Fatma, Al-Saif, Maher, Warsy, Arjumand, Khabar, Khalid SA, Hitti, Edward G
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
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Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973731/
https://ncbi.nlm.nih.gov/pubmed/24525793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.27863
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