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miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer
The activities of RNA-binding proteins are perturbed in several pathological conditions, including cancer. These proteins include tristetraprolin (TTP, ZFP36) and HuR (ELAVL1), which respectively promote the decay or stability of adenylate-uridylate-rich (AU-rich) mRNAs. Here, we demonstrated that i...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley & Sons, Ltd
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732382/ https://ncbi.nlm.nih.gov/pubmed/23401122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4178 |
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