miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer

The activities of RNA-binding proteins are perturbed in several pathological conditions, including cancer. These proteins include tristetraprolin (TTP, ZFP36) and HuR (ELAVL1), which respectively promote the decay or stability of adenylate-uridylate-rich (AU-rich) mRNAs. Here, we demonstrated that i...

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Bibliographic Details
Main Authors: Al-Ahmadi, Wijdan, Al-Ghamdi, Maha, Al-Souhibani, Norah, Khabar, Khalid SA
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2013
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Original Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732382/
https://ncbi.nlm.nih.gov/pubmed/23401122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4178
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