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RNase L down-modulation of the RNA Binding Protein, HuR, and cellular growth

Ribonuclease L (RNase L) is an intracellular enzyme that is vital in innate immunity, but also is a tumor suppressor candidate. Here, we show that over-expression of RNase L decreases cellular growth and down-modulates the RNA binding protein, HuR, a regulator of cell cycle progression and tumorigen...

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Detalhes bibliográficos
Main Authors: Al-Ahmadi, Wijdan, Al-Ghamdi, Maha, al-Haj, Latifa, Al-Mohanna, Futwan A., Silverman, Robert H., Khabar, Khalid S. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071643/
https://ncbi.nlm.nih.gov/pubmed/19252527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.16
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