Global assessment of GU-rich regulatory content and function in the human transcriptome

Unlike AU-rich elements (ARes) that are largely present in the 3′UTRs of many unstable mammalian mRNAs, the function and abundance of GU-rich elements (GRes) are poorly understood. We performed a genome-wide analysis and found that at least 5% of human genes contain GRes in their 3′UTRs with functio...

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Detalhes bibliográficos
Main Authors: Halees, Anason S, Hitti, Edward, Al-Saif, Maher, Mahmoud, Linah, Vlasova-St Louis, Irina A, Beisang, Daniel J, Bohjanen, Paul R, Khabar, Khalid SA
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225982/
https://ncbi.nlm.nih.gov/pubmed/21691152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.4.16283
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