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Curbing autophagy and histone deacetylases to kill cancer cells

Cells respond to cytotoxicity by activating a variety of signal transduction pathways. One pathway frequently upregulated during cytotoxic response is macroautophagy (hereafter referred to as autophagy). Previously, we demonstrated that pan-histone deacetylase (HDAC) inhibitors, such as the anticanc...

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Autori principali: Gammoh, Noor, Marks, Paul A., Jiang, Xuejun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973656/
https://ncbi.nlm.nih.gov/pubmed/22894919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21151
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