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Selective autophagy regulates T cell activation

T cells are essential for defense of the host against invading pathogens. Antigen activation of the T cell receptor (TCR) is required for generation of an adaptive immune response. Several groups have observed that blocking autophagy augments T cell activation, but the molecular basis of this findin...

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Autori principali: Paul, Suman, Schaefer, Brian C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494603/
https://ncbi.nlm.nih.gov/pubmed/22874554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21581
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