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Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB
The adaptor protein Bcl10 is a critically important mediator of T cell receptor (TCR)-to-NF-κB signaling. Bcl10 degradation is a poorly understood biological phenomenon suggested to reduce TCR activation of NF-κB. Here we have shown that TCR engagement triggers the degradation of Bcl10 in primary ef...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3389288/ https://ncbi.nlm.nih.gov/pubmed/22658522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.04.008 |
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