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Crystal structure of a conformation-dependent rabbit IgG Fab specific for amyloid prefibrillar oligomers

Although rabbit antibodies are widely used in research, no structures of rabbit antigen-binding fragments (Fab) have been reported. M204 is a rabbit monoclonal antibody that recognizes a generic epitope that is common to prefibrillar amyloid oligomers formed from many different amyloidogenic sequenc...

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Bibliografiske detaljer
Main Authors: Arai, Hiromi, Glabe, Charles, Luecke, Hartmut
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973424/
https://ncbi.nlm.nih.gov/pubmed/22940003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2012.08.016
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