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An arginine-aspartate network in the active site of bacterial TruB is critical for catalyzing pseudouridine formation
Pseudouridine synthases introduce the most common RNA modification and likely use the same catalytic mechanism. Besides a catalytic aspartate residue, the contributions of other residues for catalysis of pseudouridine formation are poorly understood. Here, we have tested the role of a conserved basi...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973310/ https://ncbi.nlm.nih.gov/pubmed/24371284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1331 |
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