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A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation

Archease is a 16-kDa protein that is conserved in all three domains of life. In diverse bacteria and archaea, the genes encoding Archease and the tRNA ligase RtcB are localized into an operon. Here we provide a rationale for this operon organization by showing that Archease and RtcB from Pyrococcus...

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Bibliografiske detaljer
Main Authors: Desai, Kevin K., Cheng, Chin L., Bingman, Craig A., Phillips, George N., Raines, Ronald T.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973293/
https://ncbi.nlm.nih.gov/pubmed/24435797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1375
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