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Coevolution of RtcB and Archease created a multiple-turnover RNA ligase
RtcB is a noncanonical RNA ligase that joins either 2′,3′-cyclic phosphate or 3′-phosphate termini to 5′-hydroxyl termini. The genes encoding RtcB and Archease constitute a tRNA splicing operon in many organisms. Archease is a cofactor of RtcB that accelerates RNA ligation and alters the NTP specifi...
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| Publié dans: | RNA |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604427/ https://ncbi.nlm.nih.gov/pubmed/26385509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052639.115 |
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