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Characterization of 3′-Phosphate RNA Ligase Paralogs RtcB1, RtcB2, and RtcB3 from Myxococcus xanthus Highlights DNA and RNA 5′-Phosphate Capping Activity of RtcB3

Escherichia coli RtcB exemplifies a family of GTP-dependent RNA repair/splicing enzymes that join 3′-PO(4) ends to 5′-OH ends via stable RtcB-(histidinyl-N)-GMP and transient RNA(3′)pp(5′)G intermediates. E. coli RtcB also transfers GMP to a DNA 3′-PO(4) end to form a stable “capped” product, DNA(3′...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Maughan, William P., Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621082/
https://ncbi.nlm.nih.gov/pubmed/26350128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00631-15
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