Transport properties of pancreatic cancer describe gemcitabine delivery and response

Background. The therapeutic resistance of pancreatic ductal adenocarcinoma (PDAC) is partly ascribed to ineffective delivery of chemotherapy to cancer cells. We hypothesized that physical properties at vascular, extracellular, and cellular scales influence delivery of and response to gemcitabine-bas...

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Detaylı Bibliyografya
Asıl Yazarlar: Koay, Eugene J., Truty, Mark J., Cristini, Vittorio, Thomas, Ryan M., Chen, Rong, Chatterjee, Deyali, Kang, Ya’an, Bhosale, Priya R., Tamm, Eric P., Crane, Christopher H., Javle, Milind, Katz, Matthew H., Gottumukkala, Vijaya N., Rozner, Marc A., Shen, Haifa, Lee, Jeffery E., Wang, Huamin, Chen, Yuling, Plunkett, William, Abbruzzese, James L., Wolff, Robert A., Varadhachary, Gauri R., Ferrari, Mauro, Fleming, Jason B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2014
Konular:
Clinical Medicine
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973100/
https://ncbi.nlm.nih.gov/pubmed/24614108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73455
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