Phase II Trial of Cetuximab, Gemcitabine, and Oxaliplatin Followed by Chemoradiation With Cetuximab for Locally Advanced (T4) Pancreatic Adenocarcinoma: Correlation of Smad4(Dpc4) Immunostaining With Pattern of Disease Progression

PURPOSE: This phase II trial was designed to assess the efficacy and safety of cetuximab, gemcitabine, and oxaliplatin followed by cetuximab, capecitabine, and radiation therapy in locally advanced pancreatic cancer (LAPC). PATIENTS AND METHODS: Treatment-naive eligible patients (n = 69) received in...

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Detalhes bibliográficos
Main Authors: Crane, Christopher H., Varadhachary, Gauri R., Yordy, John S., Staerkel, Gregg A., Javle, Milind M., Safran, Howard, Haque, Waqar, Hobbs, Bridgett D., Krishnan, Sunil, Fleming, Jason B., Das, Prajnan, Lee, Jeffrey E., Abbruzzese, James L., Wolff, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2011
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157965/
https://ncbi.nlm.nih.gov/pubmed/21709185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.33.8038
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