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Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues.
The drug 5-azacytidine was injected into mice to activate silent retroviral genomes. The Mov-7 and Mov-10 substrains of mice were used, each of which carries a Moloney murine leukemia provirus with mutations in the coding regions at nonidentical positions. These proviral genomes are highly methylate...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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1985
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC397280/ https://ncbi.nlm.nih.gov/pubmed/2579397 |
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