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Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues.

The drug 5-azacytidine was injected into mice to activate silent retroviral genomes. The Mov-7 and Mov-10 substrains of mice were used, each of which carries a Moloney murine leukemia provirus with mutations in the coding regions at nonidentical positions. These proviral genomes are highly methylate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jaenisch, R, Schnieke, A, Harbers, K
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1985
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC397280/
https://ncbi.nlm.nih.gov/pubmed/2579397
Etiketak: Etiketa erantsi
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