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Nucleolar Dysfunction in Huntington’s Disease
Huntington’s disease (HD) is a fatal genetic disorder characterized by triad clinical symptoms of chorea, emotional distress, and cognitive decline. Genetic mutation in HD is identified by an expansion of CAG repeats coding for glutamine (Q) in exon 1 of the huntingtin (htt) gene. The exact mechanis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972370/ https://ncbi.nlm.nih.gov/pubmed/24184605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.09.017 |
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