Nucleolar Dysfunction in Huntington’s Disease

Huntington’s disease (HD) is a fatal genetic disorder characterized by triad clinical symptoms of chorea, emotional distress, and cognitive decline. Genetic mutation in HD is identified by an expansion of CAG repeats coding for glutamine (Q) in exon 1 of the huntingtin (htt) gene. The exact mechanis...

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Bibliographic Details
Main Authors: Lee, Junghee, Hwang, Yu Jin, Ryu, Hyun, Kowall, Neil W., Ryu, Hoon
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972370/
https://ncbi.nlm.nih.gov/pubmed/24184605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.09.017
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