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Epigenetic Mechanisms of Neurodegeneration in Huntington’s Disease
Huntington’s disease (HD) is an incurable and fatal hereditary neurodegenerative disorder of mid-life onset characterized by chorea, emotional distress, and progressive cognitive decline. HD is caused by an expansion of CAG repeats coding for glutamine (Q) in exon 1 of the huntingtin gene. Recent st...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805871/ https://ncbi.nlm.nih.gov/pubmed/24006238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0206-5 |
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