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Epigenetic Mechanisms of Neurodegeneration in Huntington’s Disease

Huntington’s disease (HD) is an incurable and fatal hereditary neurodegenerative disorder of mid-life onset characterized by chorea, emotional distress, and progressive cognitive decline. HD is caused by an expansion of CAG repeats coding for glutamine (Q) in exon 1 of the huntingtin gene. Recent st...

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Autors principals: Lee, Junghee, Hwang, Yu Jin, Kim, Ki Yoon, Kowall, Neil W., Ryu, Hoon
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805871/
https://ncbi.nlm.nih.gov/pubmed/24006238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0206-5
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