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Klotho has dual protective effects on cisplatin-induced acute kidney injury
Klotho protects the kidney from ischemia-reperfusion injury, but its effect on nephrotoxins is unknown. Here we determined if Klotho protects the kidney from cisplatin toxicity. Cisplatin increased plasma creatinine and induced tubular injury, which were exaggerated in Klotho haplosufficient (Kl/+)...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972320/ https://ncbi.nlm.nih.gov/pubmed/24304882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.489 |
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