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Obesity accelerates Helicobacter felis-induced gastric carcinogenesis by enhancing immature myeloid cell trafficking and T(H)17 response

OBJECTIVE: To investigate the role of obesity-associated inflammation and immune modulation in gastric carcinogenesis during Helicobacter-induced chronic gastric inflammation. DESIGN: C57BL/6 male mice were infected with H felis and placed on a high-fat diet (45% calories from fat). Study animals we...

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Main Authors: Ericksen, Russell E, Rose, Shannon, Westphalen, Christoph Benedikt, Shibata, Wataru, Muthupalani, Sureshkumar, Tailor, Yagnesh, Friedman, Richard A, Han, Weiping, Fox, James G, Ferrante, Anthony W, Wang, Timothy C
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972255/
https://ncbi.nlm.nih.gov/pubmed/23729675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-305092
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