Conditional deletion of IkappaB-kinase beta (IKKβ) accelerates Helicobacter-dependent gastric apoptosis, proliferation and preneoplasia

BACKGROUND & AIMS: The NF-κB/IKKβ pathway has been shown to represent a key link between inflammation and cancer, inducing pro-inflammatory cytokines in myeloid cells and antiapoptotic pathways in epithelial cells. However, the role of NF-κB pathway in gastric carcinogenesis and injury has not b...

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Main Authors: Shibata, Wataru, Takaishi, Shigeo, Muthupalani, Sureshkumar, Pritchard, D. Mark, Whary, Mark T., Rogers, Arlin B., Fox, James G., Betz, Kelly S., Kaestner, Klaus H., Karin, Michael, Wang, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831162/
https://ncbi.nlm.nih.gov/pubmed/19962981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.11.054
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