Iron deficiency accelerates Helicobacter pylori–induced carcinogenesis in rodents and humans

Gastric adenocarcinoma is strongly associated with Helicobacter pylori infection; however, most infected persons never develop this malignancy. H. pylori strains harboring the cag pathogenicity island (cag(+)), which encodes CagA and a type IV secretion system (T4SS), induce more severe disease outc...

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Detalhes bibliográficos
Main Authors: Noto, Jennifer M., Gaddy, Jennifer A., Lee, Josephine Y., Piazuelo, M. Blanca, Friedman, David B., Colvin, Daniel C., Romero-Gallo, Judith, Suarez, Giovanni, Loh, John, Slaughter, James C., Tan, Shumin, Morgan, Douglas R., Wilson, Keith T., Bravo, Luis E., Correa, Pelayo, Cover, Timothy L., Amieva, Manuel R., Peek, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3533289/
https://ncbi.nlm.nih.gov/pubmed/23257361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64373
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