Depletion of Cutaneous Macrophages and Dendritic Cells Promotes Growth of Basal Cell Carcinoma in Mice

Basal cell carcinoma (BCC) belongs to the group of non-melanoma skin tumors and is the most common tumor in the western world. BCC arises due to mutations in the tumor suppressor gene Patched1 (Ptch). Analysis of the conditional Ptch knockout mouse model for BCC reveals that macrophages and dendriti...

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Autors principals: König, Simone, Nitzki, Frauke, Uhmann, Anja, Dittmann, Kai, Theiss-Suennemann, Jennifer, Herrmann, Markus, Reichardt, Holger M., Schwendener, Reto, Pukrop, Tobias, Schulz-Schaeffer, Walter, Hahn, Heidi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972151/
https://ncbi.nlm.nih.gov/pubmed/24691432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093555
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