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Patched Knockout Mouse Models of Basal Cell Carcinoma

Basal cell carcinoma (BCC) is the most common human tumor. Mutations in the hedgehog (HH) receptor Patched (PTCH) are the main cause of BCC. Due to their high and increasing incidence, BCC are becoming all the more important for the health care system. Adequate animal models are required for the imp...

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Detalhes bibliográficos
Main Authors: Nitzki, Frauke, Becker, Marco, Frommhold, Anke, Schulz-Schaeffer, Walter, Hahn, Heidi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449132/
https://ncbi.nlm.nih.gov/pubmed/23024864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/907543
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