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Precise Gene Modification Mediated by TALEN and Single-Stranded Oligodeoxynucleotides in Human Cells

The development of human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) facilitates in vitro studies of human disease mechanisms, speeds up the process of drug screening, and raises the feasibility of using cell replacement therapy in clinics. However, the study of genotype-p...

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Sonraí Bibleagrafaíochta
Main Authors: Wang, Xiaoling, Wang, Yingjia, Huang, He, Chen, Buyuan, Chen, Xinji, Hu, Jianda, Chang, Tammy, Lin, Ren-Jang, Yee, Jiing-Kuan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972112/
https://ncbi.nlm.nih.gov/pubmed/24691488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093575
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